How are donor eggs fertilized?

  1.  amanda_feelings

    Hello everyone,

    as a consequence of cancer treatments, I need to use donor eggs now. I’m married, so I’d use my husband’s sperm. But I would like to know how are donor eggs fertilized and how does egg donation work.

    Thank you very much!

    November 27, 2015 at 1:39 pm
  2. Sandra F.Sandra F.
    inviTRA's Moderator

    Dear amanda_feelings,

    Every egg donation process begins with egg retrieval via follicular puncture, which is obviously performed to the donor, who will have been previously selected so that she is compatible with the recipient (you, in this case). This is done by means of a thorough medical, psychological and genetic screening process. Then, the eggs you receive are fertilized using your husband’s sperm through two main techniques:

    Conventional in vitro fertilization: eggs are placed in special plates together with the capacitated semen sample (sperm capacitation is necessary to select only those sperm presenting the best sperm motility). Egg-sperm binding occurs spontaneously and does not require the involvement of the specialist. After a few of hours, the sample is checked to see if fertilization has occurred as expected. For being able to perform this technique, minimum requirements related to sperm concentration, motility and morphology are met.

    ICSI: sperm are selected under the microscope and are later micro-injected directly into the egg. Even though in this ase, egg-sperm binding is done manually, it should be equally checked whether fertilization has happened as expected. ICSi is indicated in cases of severe male factor and provided that the minimum criteria are met.

    Choosing between one technique or another when donor eggs are used depends on the medical history of each patient. If no specific indications are given, then conventional IVF is the first technique performed. Otherwise, ICSI is recommended mainly because higher success rates will be achieved.

    Once best quality embryos are selected according to its morphology, embryo transfer is carried out.

    Hope this helps

    December 4, 2015 at 1:59 pm
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