Miscarriage rate using donor eggs

  1.  O. S. Caulton

    Hi there! I’ve done 2 IVF cycles and both lead to failure. I’ve gone through a total of 4 miscarriages, twice after IVF and one that occurred naturally. After taking on some fertility tests, the conclusion is that I’ve got low ovarian reserve and poor-quality eggs, and that’s why I have recurrent miscarriages. Now, they told me the best thing would be using donor eggs, since mine is a typical case where donor eggs are indicated. But I want to be sure that, if I use donor eggs, miscarriage rates will shrink. Or could egg donation increase the miscarriage rate conversely? If so, I don’t wanna do it.

    December 4, 2015 at 11:50 am
  2. Sandra F.Sandra F.
    inviTRA's Moderator

    Hello O. S. Caulton,

    As ovarian reserve diminishes, egg quantity is less and the eggs available are likely to be of poor quality and carriers of genetic abnormalities. Even if a poor-quality egg was able to fertilize and therefore implant to the endometrium, the most probable outcome it that embryonic arrest occurs, which would lead to miscarriage.

    When resorting to donor-egg IVF, donor eggs instead of own eggs are used. As you may know, donor eggs come from young, healthy girls, so they are of optimal quality. And this is the reason why miscarriage rates usually shrink dramatically. Although accurate figures depend on each fertility clinic and the patient’s medical history, the average full-term pregnancy success rate of donor-egg IVF is around 40%.

    Of course, some other factors may be the cause as to why you are having recurrent miscarriages, regardless of your egg quality. For this reason, I recommend you to take a test in which the following conditions are examined: uterine alterations that hinder embryo development, thrombophilia, and immunological factors. If these factors are monitored and you use donor eggs, odds of getting pregnant in cases of low ovarian reserve are high.

    Best wishes

    December 16, 2015 at 12:11 pm
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