Which treatment should we choose with Klinefelter Syndrome?

  1.  Thomas Foster

    Hi there,

    Not too many men getting involved in here… Well, nice to meet you all! I did a karyotype analysis a few weeks ago and I’ve been detected the Klinefelter Syndrome, and therefore my azoospermia is non-obstructive (secretory) and we should use donor sperm. I’d like to know which options do we have regarding the treatment we should use (IVF, AI…) and also I want a confirmation that I have a 0 chance of having children using my own sperm, because I’ve read in some webpages that men with KS still have a very small percentage of sperm count.

    Thanks,

    Thomas

    November 5, 2015 at 4:32 pm
    Reply
  2. Sandra F.Sandra F.
    inviTRA's Moderator

    Dear Thomas,

    The Klinefelter Syndrome is a chromosomal alteration in which the affected man has more than one X chromosome, that is, XXY. Hormone levels of men with KS are below what is considered as normal. This has an impact on sperm production, leading thus to secretory or non-obstructive azoospermia.

    Only individuals with mosaic Klinefelter syndrome (where there are normal cell lines and XXY lines) may have milder signs of sperm production after doing a testicular biopsy. In such case, their sperm could be used in IVF cycles with the ICSI technique.

    In cases of zero sperm count, these man have no choice but to use donor sperm. You can choose between artificial insemination (AI) or in vitro fertilization (IVF) depending on the characteristics of your female partner. For artificial insemination by donor (AID) to be successful, the woman has to count on a normal ovarian reserve and tubal patency. Otherwise, the recommended treatment is IVF.

    Hope this helps

    November 6, 2015 at 12:51 pm
    Reply
Other topics related to this forumMessagesUpdated
Could the sperm bank accidentally mix up our donor choice? 3 12 months ago
Why is egg donation still a taboo among fertility treatments? 4 8 months, 3 weeks ago
Home sperm test kit for testing male fertility 2 1 year ago
Semen Analysis Report: high viscosity and failure to liquefy 2 8 months, 1 week ago
Insurance coverage for AI? 3 1 year, 4 months ago
Natural cure of azoospermia with ancient ayurvedic treatments 2 11 months ago
How can I get pregnant with twins? 3 1 year, 4 months ago
My period came twice in one month 2 1 year, 4 months ago
When should I test for pregnancy after blastocyst embryo transfer? 2 1 year, 1 month ago
Poor egg quality with donor eggs? 2 8 months, 3 weeks ago