By Cristina Mestre Ferrer BSc, MSc (embryologist).
Last Update: 10/17/2014

In Vitro Fertilisation (IVF) is one of the most widely used assisted reproduction‘s techniques. It consists of extracting the eggs through a follicular puncture, and then of fertilising them with the man’s sperm in the lab. Embryos are cultivated until the embryo transfer to the mother is carried out.

Thanks to this treatment, every year thousands of babies are born: it is a totally secure technique that allows to achieve the pregnancy despite man’s, woman’s or both fertility problems.

Requirements to carry out an IVF with double donation

In the situations in which it is impossible to have the patients’ gametes (egg and/or sperm), an option could be using in vitro fecundation with double donation, is to say, an IVF with eggs and sperm donor.

Oocyte donation

When it is necessary to turn to the eggs of an eggs donor, this will be a young and totally healthy woman, who gives her eggs so that a woman with difficulties in achieving the pregnancy through her own oocytes can use them.

There are different reasons for which a woman can’t use her own eggs to carry out an in vitro fertilisation. The most common are:

  • Aging eggs, for advanced maternal age.
  • Alterations or inability to ovulate.
  • Mild or severe endometriosis.
  • Tubal factor.
  • Risk of hereditary diseases being transmitted.

Sperm donation

It can happen that neither can provide the man his own spermatozoa for the fertility treatment, and he has to turn to a sperm donor. The sperm donor is a young and healthy man, with a very high seminal quality, who decides to help couples with fertility problems.

The main reasons for requiring a sperm donor are:

  • Woman who wants to be a single mother.
  • Lesbian couples.
  • Azoospermia.
  • Oligospermia.
  • Criptozoospermia.
  • Risk of transmitting a hereditary disease.

IVF with double donation's effectiveness

Success of treatment

The success rate of this technique is really high, more than a conventional IVF. Although the used technique is exactly the same, the fact of having donors increases the fertilisation’s rate and the chance of achieving a pregnancy.

Donors always are young and healthy. Moreover, they pass through several tests that guarantee they fertility is good. Sperm donors must have a high reproductive capacity, so that their seminal parameters must be far above the average to be accepted in a sperm donation‘s cycle.

FAQs from users

Is it possible to do IVF with both donor eggs and sperm?

By Andrea Rodrigo BSc, MSc (embryologist).

Yes, it is. This technique is known as double-donor IVF and is indicated in the following cases: problems in the ovaries (either because of age or other unknown causes), sperm problems (zero or low sperm count, or poor motility), and single females.

For further information, we recommend you to visit the following post: What is double-donor IVF?

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Authors and contributors

 Cristina Mestre Ferrer
BSc, MSc
Embryologist
Bachelor's Degree in Biological Sciences, Genetics & Human Reproduction from the University of Valencia (UV). Master's Degree in Biotechnology of Human Assisted Reproduction from the UV and the Valencian Infertility Institute (IVI). Embryologist at IVI Barcelona. More information
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