Effects of hCG

Human chorionic gonadotropin (hCG) as a medication is prescribed for assisted reproductive treatments in order to achieve pregnancy.

The administration of exogenous hCG may cause the next effects:

  • It has a part in follicle final maturation.
  • It causes ovulation 37 hours after its administration.

During ovulation, an egg becomes detached from the follicle.

Effects of hCG

The hCG and the LH or luteinizing hormone have common biological activity and very similar structure. Thus, if hCG is exogenously administered, it will adhere to functional LH receptors in granule cells, causing the same effects as LH.

This means that it triggers a series of reactions which lead to the degradation of the follicular wall by means of proteolytic enzymes, the release of the ovum, and the formation of the corpus luteum.

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