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How does MACS in sperm selection work?

By Leonor Ortega López B.Sc., M.Sc. (embryologist).
Last Update: 11/26/2019

MACS stands for Magnetic-activated cell sorting and consists of discarding apoptotic sperm, or select sperm that do not have fragmented DNA.

It can be used in seminal samples of patients who are going to perform both in vitro fertilization (IVF), intracytoplasmic microinjection (ICSI) and artificial insemination (AI), although its limitation is that it must be used in samples with sufficient seminal quality for the result to be optimal, as the seminal concentration decreases.

It is indicated for patients with a high percentage of spermatozoa with fragmented DNA, repeated miscarriages, poor embryo quality and low fertilization rates.

 Leonor Ortega López
Leonor Ortega López
B.Sc., M.Sc.
Embryologist
Leonor Ortega López studied Biological Sciences at the University of Valencia (Spain). She then completed a Master's Degree in Human Reproduction taught by the Spanish Fertility Society and the Complutense University of Madrid.
No: 03123-CV
Embryologist. Leonor Ortega López studied Biological Sciences at the University of Valencia (Spain). She then completed a Master's Degree in Human Reproduction taught by the Spanish Fertility Society and the Complutense University of Madrid. No: 03123-CV.