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What does vertical transmission of hepatitis B mean?

By Marta Barranquero Gómez B.Sc., M.Sc. (embryologist).
Last Update: 01/18/2022

Vertical transmission of hepatitis B refers to the spread of an infection or other disease from mother to child through the placenta or during delivery.

HBsAg is the first marker to appear in the serum of a hepatitis B infected person. In contrast, HBeAg corresponds to the replication of the virus. For this reason, when a woman presents both markers, the probability of transmitting the infection to her offspring is 65-90%.

On the other hand, these percentages are reduced to 5-30% when the woman only presents HBsAg.

 Marta Barranquero Gómez
Marta Barranquero Gómez
B.Sc., M.Sc.
Embryologist
Graduated in Biochemistry and Biomedical Sciences by the University of Valencia (UV) and specialized in Assisted Reproduction by the University of Alcalá de Henares (UAH) in collaboration with Ginefiv and in Clinical Genetics by the University of Alcalá de Henares (UAH).
License: 3316-CV
Embryologist. Graduated in Biochemistry and Biomedical Sciences by the University of Valencia (UV) and specialized in Assisted Reproduction by the University of Alcalá de Henares (UAH) in collaboration with Ginefiv and in Clinical Genetics by the University of Alcalá de Henares (UAH). License: 3316-CV.