The culture conditions, or the quality of the sperm or egg cells can result in the embryo not continuing its development towards becoming a blastocyst.
The possible causes that cause the embryo to block its development are:
- Fragmentation of double-stranded DNA that the egg is not able to repair, therefore, the embryo will not be able to activate its genome..
- Altered FISH will lead to an increase in aneuploid embryos.
- Poor oocyte quality, post-ripe eggs, eggs with endoplasmic reticulum or altered polar bodies may prevent the embryo from continuing its development.
- Genetic or chromosomal alterations present in the embryo that will make it unable to activate its genome.
Read the full article on: Why do in vitro fertilization cycles sometimes get cancelled? ( 40).
María Ortega Ortega
B.Sc., M.Sc.
Degree in Biology and Biochemistry from the University of Salamanca. She has a Master's Degree in Human Reproduction from the Complutense University of Madrid and another one in Nutrition and Health from the Open University of Catalonia.
Licence number: CLM-0180
