Immunological sterility due to anti-sperm antibodies is an entity that is rarely found as the only cause of infertility, being in most cases associated with the alteration of other factors that intervene in the probability of conceiving. These include a decrease in ovarian reserve, a tubal factor, the presence of some alteration in the cervix or endometrial cavity, alterations in seminal parameters, DNA fragmentation in the spermatozoa, etc.
In cases where anti-sperm antibodies are present in the woman's cervical mucus, sperm microinjection (ICSI) prevents the sperm from coming into contact with the antibodies and, therefore, avoids the damage they may cause. ICSI, besides allowing us to select the spermatozoa with the best motility and morphology from the male seminal sample, avoids the contact of the spermatozoa with the female cervical mucus, and in this way the male cells will not be affected by the pH, bacteria or the presence of possible antibodies. For this reason, IVF-ICSI is considered the best fertility treatment option for couples in whom we detect that anti-sperm antibodies may be hindering pregnancy.
Dr. Chavez has made several publications, courses and presentations at conferences on fertility, assisted reproduction, gynecology, both nationally and at European level. Since the opening of Ovoclinic Madrid, she is the medical director and gynecologist of the clinic.