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To what extent does it depend on the patient whether embryo implantation is successful or not? Are there any specific precautions to be taken?
By Manuel Muñoz. Last Update: 01/03/2022

There are no specific measures that patients can take, except to follow the specific indications given by their physician regarding medication. It is true that sometimes it is recommended to avoid exertion or to take relative rest after the transfer. This is a measure which, from a psychological point of view, helps patients to feel fully involved in their cycle.

How important are cytokines in the embryo implantation process?
By Manuel Muñoz. Last Update: 09/20/2011

Cytokines are proteins that regulate interactions between different cells in the body and therefore contribute to the "dialogue" between them. It is logical to think that this interaction or dialogue between the endometrium and the embryo is modulated, among others, by this set of proteins called cytokines. Their function is key, and each day it is understood a little better what is the role they play and what is their true relevance.

What are the main causes that hinder embryo implantation in an ART cycle?
By Manuel Muñoz. Last Update: 09/20/2011

There are several types of causes that can hinder the correct implantation of the embryo:

  1. Uterine problems. The presence of a uterine pathology can condition the implantation of the embryos. It is always a question of ruling out the existence of the same (polyps, myomas, intrauterine adhesions...) before carrying out a reproduction treatment.
  2. The intrinsic quality of the embryos transferred. Higher quality embryos are more likely to implant.
  3. Problems arising from the execution of assisted reproduction treatments. The clearest example is the significant elevation (more than 3000 pg/mL) of estradiol levels in the blood.
Which treatment is the most effective for a successfull embryo implantation?
By Manuel Muñoz. Last Update: 09/20/2011

The ideal treatment is the one that manages to generate good quality embryos, with no circumstances that diminish their chances of implantation. In addition, it is necessary to count on a correct transference of the same ones to the interior of the uterus.

It is important to point out that nowadays, due to the great advances in cryobiology (vitrification of oocytes and/or embryos), it has been achieved that the negative impact that the circumstances derived from controlled ovarian hyperstimulation can have is minor, given that the transfer of the embryos to a natural cycle can be deferred instead of transferring in circumstances of high levels of estrogens, a more physiological environment for embryo implantation and for which implantation in the human organism is designed.