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Does the man's age affect the quality of his sperm?

By Mark P. Trolice.
Last Update: 03/14/2019

Advanced paternal age (APA) is usually defined above age 35-40 and is associated with decreasing sperm analysis parameters. Men above age 45 have approximately 5 times as long to achieve a pregnancy compared with men less than 25 years of age. Further, there is evidence for APA increasing risk of miscarriage, birth defects, and autism. Men older than 40-45 have a twice as likely risk of an autistic child and five times higher risk of a child with schizophrenia.

Suggested for you: Male Fertility Testing – How Do You Know if You Are Infertile?.

 Mark P. Trolice
Mark P. Trolice
MD, FACOG, FACS, FACE
Reproductive Endocrinologist
Mark P. Trolice is the Director of Fertility CARE – The IVF Center and Clinical Associate Professor in the Department of Obstetrics & Gynecology (OB/GYN) at the University of Central Florida College of Medicine. He is Board-certified in REI and OB/GYN, and maintains annual recertification. His colleagues select him as Top Doctor in America® annually, one among the top 5% of doctors in the U.S.
License: ME 78893
Reproductive Endocrinologist. Mark P. Trolice is the Director of Fertility CARE – The IVF Center and Clinical Associate Professor in the Department of Obstetrics & Gynecology (OB/GYN) at the University of Central Florida College of Medicine. He is Board-certified in REI and OB/GYN, and maintains annual recertification. His colleagues select him as Top Doctor in America® annually, one among the top 5% of doctors in the U.S. License: ME 78893.
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