By Neus Ferrando Gilabert BSc, MSc (embryologist).
Last Update: 07/21/2014

Ovarian endocrine factor is one of the causes of female sterility. Any alteration in the stages of the ovarian cycle can lead to an anovulatory cycle, associated with a wide spectrum of menstrual alterations.

Every woman can be diagnosed with temporary anovulatory cycles. They should not to be mistaken for chronic anovulation, which is what causes sterility.

The different sections of this article have been assembled into the following table of contents.

Causes of anovulation

Chronic anovulation may have different causes in accordance with the classification given by the World Health Organisation (WHO):

  • Group I or hypothalamus and pituitary disfunction.
  • Group II or alteration in the hypothalamus-pituitary secretion: includes the polycystic ovarian syndrome.
  • Group III or primary or secondary ovarian failure.
  • Group V: women with hyperprolactinaemia and evident lesion in the hypothalamic-pituitary axis.
  • Group VI: women with hyperprolactinaemia that don’t present evident lesion in the hypothalamo-hypophyseal axis.
  • Group VII or amenorrhea.

Causes of menstrual irregularities

In regular menstrual cycles, there are three scenarios that may produce ovarian factor sterility. These are:

  • Occult or hidden ovarian failure.
  • Luteinised unruptured follicle syndrome (LUFS)
  • Luteal phase defect (LPD).

If a woman wants to get pregnant, is it highly recommendable to read indications for artificial insemination and in vitro fertilisation.

It is also advisable to know the results of the seminogram (evaluation of sperm quality through semen analysis).

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Authors and contributors

 Neus Ferrando Gilabert
BSc, MSc
Bachelor's Degree in Biology from the University of Valencia (UV). Postgraduate Course in Biotechnology of Human Assisted Reproduction from the Miguel Hernández University of Elche (UMH). Experience managing Embryology and Andrology Labs at Centro Médico Manzanera (Logroño, Spain). More information
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