Symptoms after embryo transfer

  1. avatar Bavna

    Hi, thank you for helping in advance. This is my first attempt at IVF.

    I got a 6-day PGD tested embryo transfer on 2/19/16 and due to take first hCG blood test on 2/29/16. Since the transfer, I am having all sorts of symptoms, nothing severe though. I had nausea, watery vaginal discharge, notice a brown blood clot (really small), sore breasts, period like cramping and legs ache. I am taking both estrogen and progesterone, so I am not raising my hopes too much. But just to be realistic, should I take a home pregnancy test in a day or two? Please suggest.

    February 24, 2016 at 4:32 am
  2. Sandra F. Sandra F.
    Fertility counselor

    Dear Bavna,

    thank you very much for joining this Forum! Well, first of all, the fact that your embryo was PGD tested does not change the potential symptoms after embryo transfer. Secondly, even though it was a 6-day embryo, my advice is that you wait up until day 10 post embryo transfer, which is to say, on 2/29/16—just 10 days after. This way you can get a more accurate result; otherwise you may get a false negative result.

    As for the symptoms you are experiencing, there is no reason to be concerned; in fact, they are the common symptoms after an embryo transfer. Breast soreness, nausea, vaginal discharge, cramping like period… Most women experience exactly those symptoms after the transfer, without it meaning that every woman has to notice something after the ET—some women just don’t have symptoms, and it doesn’t indicate that their cycle has been unsuccessful.

    If you take a pregnancy test in a day or two, as I said earlier, you can get a false negative result, because your hCG levels may not be still high enough as to be detectable. Besides, blood pregnancy tests are more accurate than HPT, so my advice is that you wait patiently during the two-week wait (2WW). I know it can become a little bit distressing, but it is worthwhile. You’d better keep your mind busy with entertaining things and continue with your normal lifestyle.

    The following article may be of interest: Symptoms after embryo transfer. There you will find, in addition to a full list with the most common symptoms, the queries of many women in your situation.

    I hope I have been able to help,

    Best wishes

    February 24, 2016 at 9:13 am
    • Hello Sandra, I was transferred 2 embryos on the 7th of April, with stomachache until day 6 post transfer. From yesterday (day 9) I’ve been having greater stomachache, back pain and bloated stomach. Depending on my position while lying on the bed or sitting I feel an itchy sensation. Today is day 10 and still noticing these symptoms. Is it normal or not?

      April 17, 2016 at 2:25 pm
    • Sandra F. Sandra F.
      Fertility counselor

      Hello Quintessential,

      Yes, they are totally normal symptoms post embryo transfer. Taking into account that it’s day 10 post embryo transfer, they could be pregnancy symptoms or also the pre-menstrual syndrome (PMS) indicating that your period is about to show up. There is a chance that they are still symptoms caused by fertility drugs.

      Be it as it may, I’m afraid you’ll have to wait up until your pregnancy test due date (beta-hCG test) to get accurate results. If you take a pregnancy test too early, you are at risk of getting a false negative result.

      I hope I have been able to help,


      April 18, 2016 at 9:10 am
  3. Hello girls, please can you give me a reply to this question? I’m very concerned because I had 3 embryos transferred on April 8 and today I’m bleeding (brown color) and feeling nausea. My beta test is next Friday (Apr. 22)… What is going on?

    April 19, 2016 at 7:09 am
    • Sandra F. Sandra F.
      Fertility counselor

      Dear Talisman,

      Given that it is day 11 post embryo transfer, they could be early pregnancy symptoms, in which case that brown discharge would be what is known as “implantation bleeding”. In other words, it could mean that you are pregnant. As long as it is a slight bleeding, there’s no reason to panic. Nausea is a common post embryo transfer symptom as well.

      On the other hand, it could be an indicator that your period is about to come, in which case it would mean that you’re not pregnant. Anyhow, I’m afraid you’ll have to wait up until your pregnancy test due date.

      Best of luck!!

      April 19, 2016 at 11:45 am
  4. Thx Sandra for your kind reply. Keep up the good work!

    April 19, 2016 at 12:31 pm
  5. Hello Sandra, thanks for your kind reply but today I’m still bleeding and I don’t know what to do. Do you think it’s my embryo? Am I expelling it or something? What can I do?

    April 20, 2016 at 8:31 am
  6. Hello, on April 13 I had two frozen embryos transferred and between 14-15th April I experienced some constipation. Should I be concerned? There’s no other pain apart from that. Thx

    April 20, 2016 at 11:06 am
    • Sandra F. Sandra F.
      Fertility counselor

      Dear eve susan,

      Although constipation is not a common symptom after embryo transfer, it might occur as a consequence of anxiety or as a side effect of fertility medications. In principle, if it lasted just one day, there is no reason to be concerned.

      Best wishes!

      April 20, 2016 at 4:22 pm
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