ICSI is an assisted reproductive technique used to overcome the following infertility problems:
- Regarding male infertility: it is used in cases of azoospermia, oligozoospermia, criptozoospermia, asthenozoospermia, teratospermia, oligoasthenozoospermia, oligoasthenoteratozoospermia, men who underwent vasectomy, men with an infectious disease (HIV, hepatitis, etc.), men who have frozen their sperm before undergoing radiotherapy or chemotherapy, or failure of ejaculation under normal conditions.
- Regarding female infertility: if a low number of oocytes is obtained after follicular puncture or egg retrieval, or if the zona pellucida is very thick after oocyte retrieval, or in cases of poor egg quality.
- Repeated failure to achieve pregnancy after several cycles of conventional in vitro fertilisation.
- Egg fertilisation failure using conventional IVF.
- Microinjection of unfertilised oocytes using conventional IVF.
- In-vitro maturation of immature oocytes.
- When a Preimplantation Genetic Diagnosis (PGD) is required in cases of couples with some genetic alteration or when it is necessary to know which ones are genetically normal embryos.
- In cases of immune infertility with a low number of antisperm antibodies and after repeated failure of previous artificial insemination cycles, or in cases of immune infertility with a high number of antisperm antibodies.