By Andrea Rodrigo BSc, MSc (embryologist).
Last Update: 04/20/2015

Menopur is a gonadotropin. This medicine is prescribed to women during controlled ovarian stimulation in an artificial insemination, in vitro fertilization or ICSI cycle. Its format is an injection.

The active ingredients of Menopur are the follicle stimulating hormone (FSH) and the luteinizing hormone (LH). It is a menotropin, also called Human Menopausal Gonadotropin or hMG. It consists of a highly purified concentration of urine from menopausal women.

Its exact composition is the following: 75 International Units (IU) of FSH in each vial and 75 International Units (IU) of LH in each vial. Besides its main components, it also contains excipients such as lactose, potassium hydroxide, polysorbate 20, and hydrochloric acid. The solvent contains sodium chloride, diluted hydrochloric acid, and water for injection.

Presentation

There are two main containers of Menopur, which include:

  • A package of 5 lyophilized vials (2 ml glass ampoules: dry substance) and 5 glass ampoules of 1 ml (solvent).
  • A package of 10 lyophilized vials (2 ml glass ampoules: dry substance) and 10 glass ampoules of 1 ml (solvent).

Menopur vial

Approximate price

Price may vary slightly but is, usually, the following:

  • Package of 5 vials: 138,94€. Reduced contribution.
  • Package of 10 vials: 222,45€. Hospital diagnoses. Reduced contribution.

Indications

Menopur is prescribed during assisted reproduction treatments, in the following cases:

  • Female sterility due to hypo or normogonadotropic ovarian failure: follicular growth stimulation.
  • Male sterility due to hypo or normogonadotropic hypogonadism: it is combined with hCG to stimulate the spermatogenesis (creation of spermatozoids).

Before using it, you should mix the dry substance with the solvent. It is administered via an intramuscular or subcutaneous injection.

Contraindications

The consumption of Menopur can be dangerous in some cases:

Women should not take this medication in the following situations:

  • Breast, uterine or ovarian cancer.
  • Increase of the size of the ovaries or ovarian cysts not caused by PCOS (polycystic ovarian syndrome).
  • Malformations of sexual organs which prevent natural pregnancy.
  • Vaginal bleeding of unknown origin.
  • Uterine fibroids.
  • Pregnancy or breastfeeding period.
  • Early menopause.

Menopur

Men with prostate carcinoma or testicular tumours should not take Menopur.

You should be careful while taking Menopur and consult your doctor if you feel any of the following symptoms:

  • Abdominal pain.
  • Swelling of the abdomen.
  • Nausea, vomiting, and/or diarrhoea.
  • Weight gain.
  • Difficulty breathing.
  • Decrease in amount of urine.

Additional information

Interactions with other medicinal products have not been reported. In infertile men, hMG can be conjointly administered with hCG.

Menopur should be kept protected from light, at a temperature not exceeding 25°C, and out of reach of children. It is only sold with a medical prescription.

Information published here should not, in any case, substitute the doctor’s indications.

Information extracted from Vademécum (treaty containing the composition, indications, side effects, etc. of each medicine available in the market).

Menopur is usually sold in Spain.

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Authors and contributors

 Andrea Rodrigo
BSc, MSc
Embryologist
Bachelor's Degree in Biotechnology from the Polytechnic University of Valencia. Master's Degree in Biotechnology of Human Assisted Reproduction from the University of Valencia along with the Valencian Infertility Institute (IVI). Postgraduate course in Medical Genetics. More information
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