By Neus Ferrando Gilabert BSc, MSc (embryologist).
Last Update: 05/05/2014

Recombinant FSH (r-FSH) is prescribed for ovulation induction in assisted reproductive treatments such as artificial insemination, conventional IVF, or ICSI.

It is made from 100% follicle-stimulating hormone (FSH). The difference between this preparation and other medications containing FSH is the term recombinant, which means that it is produced in a laboratory. It is a lab creation, while other medications come from organic materials.

For the assisted reproductive treatments, the usually prescribed medicines containing recombinant FSH are Gonal and Puregon. There is also another drug known as Pergoveris, which contains 150 IU recombinant FSH and 75 IU recombinant LH.

Recombinant follicle-stimulating hormone

Its main advantage if compared to other medications containing FSH is its high level of purification. Since it is produced specifically, it does not contain traces of other hormones but it is made from 100% FSH. For the same reason, its main drawback is that it is more expensive than natural FSH, which has been previously purified.

Other parameters are exactly the same as other medications containing purified FSH, that is to say, its side effects and indications are those of FSH.

Authors and contributors

 Neus Ferrando Gilabert
BSc, MSc
Bachelor's Degree in Biology from the University of Valencia (UV). Postgraduate Course in Biotechnology of Human Assisted Reproduction from the Miguel Hernández University of Elche (UMH). Experience managing Embryology and Andrology Labs at Centro Médico Manzanera (Logroño, Spain). More information