Rachele Pandolfi M.Sc., Ph.D.

Educational background

• Master's Degree in Human Reproduction (Madrid)
• PhD in Biomedical Research (UCM, Madrid)
• Bachelor's Degree in Biomolecular Sciences and Technologies (Master's Degree in Biology and Biochemistry, according to ANECA conversion to Spanish system); Pisa, Italy)
• First College Cycle in Molecular Biological Sciences (Bachelor's Degree in Biology and Biochemistry, according to ANECA conversion to Spanish system); Pisa, Italy)

Professional experience

• Embryologist at Clínica Tambre (2017-present)
• Postdoctorate researcher at the Complutense University of Madrid (2016)
• Pre- and post-doctorate Researcher at Instituto de investigación Sanitaria de Getafe (2015)
• Pre-doctorate researcher at Centro Nacional de Biotecnología de Madrid (2011-2012)
• Member of research team at Unidad de Enfermedades Metabólicas y Diabéticas del Hospital Universitario de Pisa, Italia (2010-2011)
• Member of research team at Instituto de Fisiología Clínica del Consejo Nacional de Investigación (CNR), Pisa, Italia (2008)

Scientific community involvement

1. Effects of quercetin in a rat model of hemorrhagic traumatic shock and reperfusion. Chamorro V†., Pandolfi R†., Moreno L., Barreira B., Martínez-Ramas A., Morales-Cano D., Ruiz-Cabello J., Lorente J.A., Duarte J., Cogolludo Á., Alvarez-Sala J.L., Perez-Vizcaino F. Molecules 2016; 21(12): 1739. †Both authors contributed equally.
2. Role of acid sphingomyelinase and IL-6 as potential novel mediators of endotoxin-induced pulmonary vascular dysfunction. Pandolfi R., Barreira B., Moreno E., Lara-Acedo V., Morales-Cano D., Martínez-Ramas A., de Olaiz Navarro B., Herrero R., Lorente JA., Cogolludo Á., Pérez-Vizcaíno F., Moreno L. Thorax 2016 Jul 27. doi: 10.1136/thoraxjnl-2015-208067.
3. Activation of PPARβ/δ prevents hyperglycaemia-induced impairment of Kv7 channels and cAMP-mediated relaxation in rat coronary arteries. Morales-Cano D., Moreno L., Barreira B., Briones AM., Pandolfi R., Moral-Sanz J., Callejo M., Mondejar-Parreño G., Cortijo J., Salaices M., Duarte J., Perez-Vizcaino F., Cogolludo A. Clin Sci (Lond) 2016; 130(20):1823-36.
4. Kv7 channels critically determine coronary artery reactivity: left-right differences and downregulation by hyperglycemia. Morales-Cano D., Barreira B, Moreno L., Pandolfi R., Jimenez R., Villamor E., Duarte J., Perez-Vizcaino F., Cogolludo A. Cardiovascular Res. 2015; 106(1):98-108.
5. The flavonoid quercetin reverses pulmonary hypertension in rats. Morales-Cano D., Menendez C., Moreno E., Moral-Sanz J., Barreira B., Galindo P., Pandolfi R., Jimenez R., Moreno L., Cogolludo A., Duarte J., Perez-Vizcaino F. PLoS One 2014; 9 oxygen (12): e114492.
6. Ceramide mediates acute sensing in vascular tissues. Moreno L., Moral-Sanz J., Morales-Cano D., Barreira B., Moreno E., Ferrarini A., Pandolfi R., Ruperez F., Sanchez-Luna M., Villamor E., Perez-Vizcaíno F., Cogolludo A. Antioxidants & Redox Signaling. 2014; 20(1):1-14.
7. A GPI anchor explains the unique biological features of the common NKG2D-ligand allele MICA*008. Ashiru O., López-Cobo S., Fernández-Messina L., Pontes-Quero S., Pandolfi R., Reyburn HT., Valés-Gómez M. Biochem J. 2013; 454(2):295-302.
8. Evidence for a role of frataxin in pancreatic islets isolated from multi-organ donor with and without type 2 diabetes mellitus. Del Guerra S., D'Aleo V., Gualtierotti G., Pandolfi R., Boggi U., Vistoli F., Barnini S., Filipponi F., Del Prato S., Lupi R. Horm Metab Res. 2012 Jun;44(6):471-5.

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