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How many IVF cycles should you do before using donor eggs?

By Mark P. Trolice M.D., F.A.C.O.G., F.A.C.S., F.A.C.E. (reproductive endocrinologist).
Last Update: 09/04/2018

This is an extremely difficult question to answer because Fertility is a physical, emotional, and financial investment. Unless a woman is in menopause, one can never definitively provide a 0% chance for pregnancy using her eggs. However, as a woman ages, particularly above age 39 along with very poor ovarian age testing (ultra low AMH and/or elevated FSH), the prognosis for success with IVF becomes very poor.

So, there is no absolute number of IVF cycles to recommend undergoing before moving to egg donation. Nevertheless, one should consider egg donation if her IVF cycle was cancelled due to a poor response or a low number of eggs were retrieved despite a high dose of stimulation with poor embryo development.

 Mark P. Trolice
Mark P. Trolice
M.D., F.A.C.O.G., F.A.C.S., F.A.C.E.
Reproductive Endocrinologist
Mark P. Trolice is the Director of Fertility CARE – The IVF Center and Clinical Associate Professor in the Department of Obstetrics & Gynecology (OB/GYN) at the University of Central Florida College of Medicine. He is Board-certified in REI and OB/GYN, and maintains annual recertification. His colleagues select him as Top Doctor in America® annually, one among the top 5% of doctors in the U.S.
License: ME 78893
Reproductive Endocrinologist. Mark P. Trolice is the Director of Fertility CARE – The IVF Center and Clinical Associate Professor in the Department of Obstetrics & Gynecology (OB/GYN) at the University of Central Florida College of Medicine. He is Board-certified in REI and OB/GYN, and maintains annual recertification. His colleagues select him as Top Doctor in America® annually, one among the top 5% of doctors in the U.S. License: ME 78893.