Yes, it would be possible to perform a biopsy of the first polar body of the egg for the purpose of genetic analysis. In this case, it would be a preconception genetic study (before the egg is fertilized by the sperm). Therefore, this study of the polar body could provide information on the genetic status of the egg, but it cannot assess whether the future embryo (once fertilization has occurred) will have any genetic abnormalities of paternal origin.
For all these reasons, this technique is not at all common, since it is more common to perform preimplantation genetic testing (PGT) on embryos, performing the biopsy when they are in the blastocyst stage.
Read the full article on: What is the procedure for pre-implantation genetic diagnosis? ( 62).
Silvia Azaña Gutiérrez
B.Sc., M.Sc.
Graduate in Health Biology from the University of Alcalá and specialized in Clinical Genetics from the same university. Master in Assisted Reproduction by the University of Valencia in collaboration with IVI clinics.
License: 3435-CV
