Obviously, the main advantage of ART is that it gives you the chance to have a baby. On the other hand, the most common disadvantage is associated with fertility drugs, due to the side effects they can cause: headache, bloating, nausea, vaginal bleeding/spotting...
However, fertility drugs are commonly the first choice because of their relative convenience, especially for IVF.
Secondly, reproductive surgery, required to correct anatomical abnormalities or clear blockages in the man or the woman, are usually invasive, which increases their risk, recovery time and cost. On the other hand, they help increase the chances of getting pregnant.
Perhaps the main disadvantage of all infertility treatments is related to the financing options, since they are not always covered by insurance. Also, in the case of IVF, the likelihood of having twins is higher if multiple embryo transfers are chosen.