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What is the relationship between systemic lupus erythematosus and vitamin D?

By Silvia Azaña Gutiérrez.
Last Update: 11/08/2021

Vitamin D deficiency is more common in people affected by this pathology than in healthy individuals. A lower sun exposure due to the photosensitivity of these patients, and an inability to produce active vitamin D due to renal dysfunction, could explain these findings.

Regarding vitamin D supplementation in these patients, for its immunomodulatory effect, there are contradictory results. While some studies have found no clear relationship in disease activity and serology with vitamin D supplementation, other studies have described a reduction in disease activity due to an immunosuppressive and anti-inflammatory effect.

Suggested for you: Does vitamin D influence pregnancy and fertility?.

 Silvia Azaña Gutiérrez
Silvia Azaña Gutiérrez
BSc, MSc
Embryologist
Graduate in Health Biology from the University of Alcalá and specialized in Clinical Genetics from the same university. Master in Assisted Reproduction by the University of Valencia in collaboration with IVI clinics.
License: 3435-CV
Embryologist. Graduate in Health Biology from the University of Alcalá and specialized in Clinical Genetics from the same university. Master in Assisted Reproduction by the University of Valencia in collaboration with IVI clinics. License: 3435-CV.