Vitamin D deficiency is more common in people affected by this pathology than in healthy individuals. A lower sun exposure due to the photosensitivity of these patients, and an inability to produce active vitamin D due to renal dysfunction, could explain these findings.
Regarding vitamin D supplementation in these patients, for its immunomodulatory effect, there are contradictory results. While some studies have found no clear relationship in disease activity and serology with vitamin D supplementation, other studies have described a reduction in disease activity due to an immunosuppressive and anti-inflammatory effect.
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