Fluorescent in-situ hybridization (FISH) makes it possible to detect chromosomal diseases such as Down's syndrome (trisomy 21) or Klinefelter's syndrome (extra X chromosome).
In the first example, a healthy male embryo is observed, with 2 copies of chromosome 21 and one copy for each of the sex chromosomes (XY). Secondly, the embryo has 3 copies of chromosome 21, resulting in a child with Down syndrome. Finally, the embryo is also male, but with an extra X chromosome, which means that the future baby will have Klinefelter's syndrome.
Read the full article on: The PGD Process Step by Step ( 62).
By Amel Khelifi Schreiber B.Sc., M.Sc., Ph.D. (embryologist), Antonio Alcaide Raya B.Sc., M.Sc., Ph.D. (senior embryologist), Gustavo Daniel Carti M.D. (gynecologist), Zaira Salvador B.Sc., M.Sc. (embryologist) and Romina Packan (invitra staff).
Last Update: 12/07/2020