The drug Gonal-f 75, is a drug containing Folitropin alpha, recombinant human follicle stimulating hormone (r-hFSH) produced in Chinese hamster ovary cells (CHO) by recombinant DNA technology. Each vial of Gonal-f 75, contains 5.5 micrograms of Folitropin alpha, equivalent to 75 IU. Therefore, each ml of the reconstituted solution in a single freeze-dried vial (powder) contains 75 IU.
Gonal-f 75 acts by producing a multiple follicular development in the ovary of women subjected to ovarian stimulation for assisted reproduction techniques (ART), such as in vitro fertilization (IVF), insemination or ovulation induction. But it is also used to stimulate spermatogenesis in men with hypogonadotropic hypogonadism.
Gonal-f 75 should be kept at a temperature not exceeding 25ºC; therefore, in hot periods such as spring or summer it is preferable to keep it in the refrigerator.
This drug should be kept with the original packaging if possible to protect it from light and above all, like any medicine, keep it out of the reach of children. In addition, it should not be used after the expiry date (it could lose its function) and should not be used if there are any visible signs of deterioration in the freeze-dried product (powder).
When preparing the gonal solution, the recommendation is to use it immediately and not to postpone its use for more than 24 hours.