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How many times should I try IVF treatment before resorting to oocyte donation?

By Mark P. Trolice M.D., F.A.C.O.G., F.A.C.S., F.A.C.E. (reproductive endocrinologist).
Last Update: 03/04/2022

It is difficult to give an answer to this question, since fertility is an investment in physical, emotional and economic terms. Except in cases of menopause, it can never be said that the success rate with a woman's own eggs is 0%. However, as age advances, especially if the woman is 39 years old and, in addition, the results of an ovarian reserve test are unsatisfactory (very low AMH values and/or elevated FSH), the chances of success with IVF are slim.

Therefore, it is not possible to recommend a certain number of IVF cycles before resorting to egg donation. In any case, egg donation should be chosen if a previous IVF cycle has had to be cancelled because of low response or because the number of oocytes obtained is very low and the embryo development is inadequate despite the use of a high dose of medication.

 Mark P. Trolice
Mark P. Trolice
M.D., F.A.C.O.G., F.A.C.S., F.A.C.E.
Reproductive Endocrinologist
Mark P. Trolice is the Director of Fertility CARE – The IVF Center and Clinical Associate Professor in the Department of Obstetrics & Gynecology (OB/GYN) at the University of Central Florida College of Medicine. He is Board-certified in REI and OB/GYN, and maintains annual recertification. His colleagues select him as Top Doctor in America® annually, one among the top 5% of doctors in the U.S.
License: ME 78893
Reproductive Endocrinologist. Mark P. Trolice is the Director of Fertility CARE – The IVF Center and Clinical Associate Professor in the Department of Obstetrics & Gynecology (OB/GYN) at the University of Central Florida College of Medicine. He is Board-certified in REI and OB/GYN, and maintains annual recertification. His colleagues select him as Top Doctor in America® annually, one among the top 5% of doctors in the U.S. License: ME 78893.