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Is hypospadias hereditary?

By Marta Barranquero Gómez.
Last Update: 06/02/2021

The exact cause of hypospadias is not known exactly, but there is some link to genetics. For this reason, some studies show that hypospadias is hereditary.

Specifically, the genetic cause of hypospadias would be a mutation in a gene, leading to a lower concentration of androgen receptors. However, it is not possible to state that this congenital malformation in the location of the urethral opening is genetic.

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 Marta Barranquero Gómez
Marta Barranquero Gómez
Embryologist
Graduated in Biochemistry and Biomedical Sciences by the University of Valencia (UV) and specialized in Assisted Reproduction by the University of Alcalá de Henares (UAH) in collaboration with Ginefiv and in Clinical Genetics by the University of Alcalá de Henares (UAH).
License: 3316-CV
Embryologist. Graduated in Biochemistry and Biomedical Sciences by the University of Valencia (UV) and specialized in Assisted Reproduction by the University of Alcalá de Henares (UAH) in collaboration with Ginefiv and in Clinical Genetics by the University of Alcalá de Henares (UAH). License: 3316-CV.