The premature interruption and termination of pregnancy not only has a physical and physiological impact on the pregnant woman, but is also often accompanied by a strong psychological impact.
Women who have suffered a miscarriage are recommended to have recovered in all these aspects before undergoing a new embryo transfer. If there are no signs of any complications, it is advisable to wait at least one complete menstrual cycle before starting the preparation for the next transfer.
For this reason, it is really important to evaluate each case in a personalized way, through a medical evaluation, but also taking into account the psychological state of the patient.
Normally, before starting another hormonal treatment, it is necessary to complete the study with specific examinations of the uterine, infectious, hematological or immunological factor, which will allow us to elucidate the reason for the previous loss.
Performing the necessary tests and trying to identify the cause of the miscarriage allows us to apply additional corrective measures if necessary in the next treatment. The causes of miscarriage are usually due to:
- The genetics of the embryo, i.e. due to alterations in the karyotype of one or both parents and chromosomal alterations, often due to advanced maternal age and/or pathologies in the semen. This can be studied by means of some tests such as preimplantation genetic tests (PGT-A, PGT-SR and PGT-M).
- Immunological alterations in the pregnant woman - which can be studied by performing an immunological test (im Map) - or coagulation problems.
- Infections during the 1st trimester of gestation.
- Uterine malformations.
In other cases, the causes are unknown, i.e., no apparent cause can be found to explain the miscarriage. Thanks to the constant technological advances in Assisted Reproduction, it is becoming more and more probable to find out the cause of the miscarriage.
