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Is it possible to perform a polar corpuscle biopsy?

By Zaira Salvador B.Sc., M.Sc. (embryologist).
Last Update: 08/09/2018

Although the most common procedure in PGD is to carry out a genetic analysis of the embryos, there is also the possibility of analysing the genetic content of the eggs obtained for IVF by means of a biopsy of the polar corpuscle.

The polar corpuscles are cells with no function that are formed during meiosis and disappear instantly after fertilization. Therefore, the polar corpuscle biopsy is performed before fertilization takes place. In this way, the eggs with the best possibilities of achieving a good development of the pregnancy are selected.

The analysis of one of these cells will not affect the future development of the embryo. However, it will not be possible to detect anomalies that occur after fertilization nor will it provide genetic information of paternal origin, only of maternal origin.

 Zaira Salvador
Zaira Salvador
B.Sc., M.Sc.
Embryologist
Bachelor's Degree in Biotechnology from the Technical University of Valencia (UPV). Biotechnology Degree from the National University of Ireland en Galway (NUIG) and embryologist specializing in Assisted Reproduction, with a Master's Degree in Biotechnology of Human Reproduction from the University of Valencia (UV) and the Valencian Infertility Institute (IVI)
License: 3185-CV
Embryologist. Bachelor's Degree in Biotechnology from the Technical University of Valencia (UPV). Biotechnology Degree from the National University of Ireland en Galway (NUIG) and embryologist specializing in Assisted Reproduction, with a Master's Degree in Biotechnology of Human Reproduction from the University of Valencia (UV) and the Valencian Infertility Institute (IVI) License: 3185-CV.