Klinefelter syndrome or 47,XXY is a genetic abnormality that occurs as a consequence of an incorrect division of homologous chromosomes during meiosis, which give raise to the gametes of one of the parents. It can also occur during the first divisions of the zygote.
Males affected by it suffer from hypogonadotropic hypogonadism, gynecomastia, learning disabilities, and infertility. It is the most common genetic disease in males. Some men, however, do not have symptoms, and they don't know that they have this condition until they are adults and have infertility issues.
Read the full article on: Klinefelter Syndrome (XXY Syndrome) – Symptoms, Causes & Fertility ( 30).
José Luis de Pablo
B.Sc., M.Sc., Ph.D.
Senior Clinical Embryologist on Fertility Madrid and ART Reproduccion
Double Degree in Biology and Biochemistry from the University of Navarra. Master’s Degree about the Theoretical Basis and Laboratory Procedures in Assisted Reproduction from the University of Valencia (UV). Senior Clinical Embryologist from the ESHRE and ASEBIR Certification in Clinical Embryology. More than 15 years of experience as the director of IVF labs.
