Assisted Hatching (AH) is a state-of-the-art technique that is used both in conventional IVF an ICSI procedures. It involves the artificial disruption of the ZP (zona pellucida) after the egg is fertilized in the laboratory.
AH is performed after IVF and ICSI procedures, right before the embryo transfer. The embryologist creates a small hole in the ZP by means of micromanipulation under a microscope. By doing this, we make it easier for the embryo to hatch out of the zona pellucida and implant to the uterine lining.
According to the ASRM (American Society for Reproductive Medicine), it is used in cases of women with advanced maternal age, poor embryo quality or after the failure of two or more previous IVF cycles.