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When PGD/PGS is required, what is better, ICSI or IVF?

By Rebeca Reus BSc, MSc (embryologist).
Last Update: 04/24/2018

If PGD (preimplantation genetic diagnosis) is to be used as well, egg fertilization is done via ICSI to avoid harmful interferences with PGD outcomes.

In IVF procedures, a percentage of the sperms that tried to penetrate the egg remain adhered to its surface. Because of that, some of their genetic material can be dragged during the embryo biopsy for PGD, which could alter the final result of this technique.

 Rebeca Reus
Rebeca Reus
BSc, MSc
Embryologist
Degree in Human Biology (Biochemistry) from the Pompeu Fabra University (UPF). Official Master's Degree in Clinical Analysis Laboratory from the UPF and Master’s Degree about the Theoretical Basis and Laboratory Procedures in Assisted Reproduction from the University of Valencia (UV).
Embryologist. Degree in Human Biology (Biochemistry) from the Pompeu Fabra University (UPF). Official Master's Degree in Clinical Analysis Laboratory from the UPF and Master’s Degree about the Theoretical Basis and Laboratory Procedures in Assisted Reproduction from the University of Valencia (UV).