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Can biochemical abortion only occur after IVF?

By Juan José Espinós Gómez M.D., Ph.D. (gynecologist).
Last Update: 05/05/2025

Biochemical miscarriage is understood to be when there is a positive pregnancy test (preferably performed on blood), and the pregnancy is lost without being able to be evidenced by imaging techniques (basically transvaginal ultrasound).

This situation is not inherent to in vitro fertilization or other assisted reproduction techniques, but it is more common to detect it in these situations. The reason for this is that after assisted reproductive techniques, a blood pregnancy test will almost always be performed. In couples seeking a spontaneous pregnancy, it is detected less frequently because the pregnancy test is not systematically performed before menstruation, so this situation goes unnoticed. It would correspond to those cases in which there is some menstrual delay, but menstruation ends up appearing (and a pregnancy test has not been performed or it has been performed in urine, and given that its detection level is lower, it comes out negative). The latter is what we would call in medicine a false negative test. In general, these delays are usually attributed to some state of stress or anxiety.

 Juan José  Espinós Gómez
Juan José Espinós Gómez
M.D., Ph.D.
Gynecologist
Dr. Juan José Espinós Gómez has a degree in Medicine from the Central University of Barcelona - Reus - and has been awarded the Outstanding Graduate Award.
Licence number: 080823651
Gynecologist. Dr. Juan José Espinós Gómez has a degree in Medicine from the Central University of Barcelona - Reus - and has been awarded the Outstanding Graduate Award. Licence number: 080823651.