Although the most common treatment for removing fibroids is surgical, GnRH agonist analogs can also serve as drug treatment to reduce the size of these fibroids.
Due to their effects, GnRH agonists cause a state of hypogonadotropic hypogonadism with very low estradiol values in women. This can help reduce fibroids and possible associated symptoms such as bleeding.
However, these drugs have unwanted side effects, and, after stopping treatment, the fibroids may grow back. For this reason, GnRH agonists are only used where indicated and as a pre-surgical step to facilitate surgery.
Suggested for you: GnRH Analogs – Indications & Use.