Certified Medical Magazine by WMA, ACSA, AACI
FAQs
12
0

Is IVF the treatment for Y chromosome microdeletions?

By Silvia Azaña Gutiérrez B.Sc., M.Sc. (embryologist).
Last Update: 08/02/2022

In vitro fertilization (IVF), specifically by intracytoplasmic sperm injection (ICSI), may be the solution for patients with Y chromosome microdeletions to have children.

However, ICSI can only be performed if sperm can be obtained from the male (either from the ejaculate or by testicular biopsy), which is more frequent in the case of microdeletions in the AZFc region of the Y chromosome.

In this case, it is very important that patients also receive genetic counseling, as the male offspring will inherit the paternal Y chromosome microdeletions.

On the other hand, in the event that sperm cannot be obtained, patients with Y chromosome microdeletions can opt for sperm donation or adoption to become parents.

 Silvia Azaña Gutiérrez
Silvia Azaña Gutiérrez
B.Sc., M.Sc.
Embryologist
Graduate in Health Biology from the University of Alcalá and specialized in Clinical Genetics from the same university. Master in Assisted Reproduction by the University of Valencia in collaboration with IVI clinics.
License: 3435-CV
Embryologist. Graduate in Health Biology from the University of Alcalá and specialized in Clinical Genetics from the same university. Master in Assisted Reproduction by the University of Valencia in collaboration with IVI clinics. License: 3435-CV.