Kartagener's syndrome is an autosomal recessive genetic disorder that affects ciliary movement in general, producing bronchiectasis and sinusitis due to poor mucus elimination due to ciliary malfunction. This syndrome was discovered by Manes Kartagener in 1933, who gave his name to this syndromic condition which, by affecting ciliary movement, also affects the mobility of the sperm flagellum.
In this sense, the spermatozoon that is alive and of adequate morphology does not have the capacity to move, this is what we know as asthenozoospermia. Pregnancy in these cases is impossible because the sperm cannot reach the egg on its long journey from the vagina to fertilise the egg in the fallopian tube, unless an assisted reproduction technique is used.
In this way, by taking a semen sample, the lack of displacement is confirmed in live and morphologically normal spermatozoa. In the laboratory, using the ICSI technique, the sperm is brought into contact with the egg in order to achieve fertilisation and, therefore, pregnancy.