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What effect do gonadotropin-releasing hormone agonists have?

By Zaira Salvador.
Last Update: 03/12/2019

The main effects produced by the use of analogs that are GnRH agonists are, on the one hand, the initial release of gonadotropins (flare-up effect) and then blocking the release of these gonadotropins, preventing the communication between the pituitary gland and the ovary so that there is no follicular development or ovulation.

All this occurs temporarily when the reserve of FSH and LH in the pituitary is empty. Normally, the total blockage of GnRH receptors occurs between 5-10 days after the first administration of the agonist.

Suggested for you: GnRH Analogs – Indications & Use.

 Zaira Salvador
Zaira Salvador
BSc, MSc
Embryologist
Bachelor's Degree in Biotechnology from the Technical University of Valencia (UPV). Biotechnology Degree from the National University of Ireland en Galway (NUIG) and embryologist specializing in Assisted Reproduction, with a Master's Degree in Biotechnology of Human Reproduction from the University of Valencia (UV) and the Valencian Infertility Institute (IVI)
License: 3185-CV
Embryologist. Bachelor's Degree in Biotechnology from the Technical University of Valencia (UPV). Biotechnology Degree from the National University of Ireland en Galway (NUIG) and embryologist specializing in Assisted Reproduction, with a Master's Degree in Biotechnology of Human Reproduction from the University of Valencia (UV) and the Valencian Infertility Institute (IVI) License: 3185-CV.
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