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What genetic causes are associated with azoospermia?

By Sergio Rogel Cayetano.
Last Update: 09/25/2020

There are multiple genetic causes that can lead to azoospermia or the absence of sperm in the semen. Below are the most well known:

Alterations in the karyotype
sometimes the testicle is not formed correctly.
Y chromosome micordelections
affects the genes that code for sperm production, which can lead to azoospermia.
Cystic Fibrosis
This genetic disease is characterized by microtubule obstructions, which can lead to azoospermia.
Other problems
Multiple genes are involved in sperm generation. The failure of one or more of them, sometimes difficult to detect, can be linked to azoospermia.
Imagen: genetic causes associated with azoospermia

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 Sergio Rogel Cayetano
Sergio Rogel Cayetano
MD
Gynecologist
Bachelor's Degree in Medicine from the Miguel Hernández University of Elche. Specialist in Obstetrics & Gynecology via M. I. R. at Hospital General de Alicante. He become an expert in Reproductive Medicine by working at different clinics of Alicante and Murcia, in Spain, until he joined the medical team of IVF Spain back in 2011.
License: 03-0309100
Gynecologist. Bachelor's Degree in Medicine from the Miguel Hernández University of Elche. Specialist in Obstetrics & Gynecology via M. I. R. at Hospital General de Alicante. He become an expert in Reproductive Medicine by working at different clinics of Alicante and Murcia, in Spain, until he joined the medical team of IVF Spain back in 2011. License: 03-0309100.
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