The main causes of children born with Klinefelter syndrome are errors during meiosis, a process required for the production of male and female gametes (egg and sperm cells).
As a result, and due to a nondisjunction of a pair of chromosomes during cell division, the child has an extra X chromosome. Subsequently, when this gamete meets a gamete of the opposite sex after fertilization, the resulting embryo will have the XXY trisomy, which is the most common genotype of males affected by KS.
Read the full article on: Klinefelter Syndrome (XXY Syndrome) – Symptoms, Causes & Fertility ( 30).
By Estefanía Rodríguez Ferradas M.D., M.Sc., Ph.D. (gynecologist), José Luis de Pablo B.Sc., M.Sc., Ph.D. (senior clinical embryologist), Zaira Salvador B.Sc., M.Sc. (embryologist) and Sandra Fernández B.A., M.A. (fertility counselor).
Last Update: 04/10/2018
