What is a chromosomal translocation?

By (psychologist).
Last Update: 03/11/2022

Chromosomal translocation is a structural chromosomal alteration characterized by the exchange of fragments between two chromosomes. If this exchange of segments occurs between non-homologous chromosomes, it is known as a reciprocal translocation.

On the other hand, if what happens is that there is a fusion of the centromeres of chromosomes 13,14,15,21, and 22, it would correspond to a Robertsonian translocation.

Frequently, those carriers of translocation have difficulty achieving a pregnancy. Chromosomal translocations are associated with oligozoospermia (low sperm concentration) problems in men. In addition, a translocation in women can lead to an increased risk of miscarriage and female infertility.

Imagen: Chromosomal translocation

If one or both members of the couple have a chromosomal translocation, it is advisable to resort to in vitro fertilization (IVF) treatment with preimplantation genetic diagnosis (PGD) to achieve your desired pregnancy.

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Author

 Cristina  Algarra Goosman
Cristina Algarra Goosman
B.Sc., M.Sc.
Psychologist
Graduated in Psychology by the University of Valencia (UV) and specialized in Clinical Psychology by the European University Center and specific training in Infertility: Legal, Medical and Psychosocial Aspects by University of Valencia (UV) and ADEIT.
More information about Cristina Algarra Goosman
Member number: CV16874

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