What is a chromosomal translocation?
Chromosomal translocation is a structural chromosomal alteration characterized by the exchange of fragments between two chromosomes. If this exchange of segments occurs between non-homologous chromosomes, it is known as a reciprocal translocation.
On the other hand, if what happens is that there is a fusion of the centromeres of chromosomes 13,14,15,21, and 22, it would correspond to a Robertsonian translocation.
Frequently, those carriers of translocation have difficulty achieving a pregnancy. Chromosomal translocations are associated with oligozoospermia (low sperm concentration) problems in men. In addition, a translocation in women can lead to an increased risk of miscarriage and female infertility.
If one or both members of the couple have a chromosomal translocation, it is advisable to resort to in vitro fertilization (IVF) treatment with preimplantation genetic diagnosis (PGD) to achieve your desired pregnancy.
