Yes. Losses of small fragments of genetic material in the AZF region of the Y chromosome cause alterations in the process of sperm formation (spermatogenesis). As a consequence, it is possible that men with microdeletions of the Y chromosome have a lower concentration of sperm in the ejaculate, especially if the microdeletions affect the AZFc region.
Read the full article on: What Diseases Are Associated with Oligospermia? ( 69).
Marta Barranquero Gómez
B.Sc., M.Sc.
Graduated in Biochemistry and Biomedical Sciences by the University of Valencia (UV) and specialized in Assisted Reproduction by the University of Alcalá de Henares (UAH) in collaboration with Ginefiv and in Clinical Genetics by the University of Alcalá de Henares (UAH).
License: 3316-CV