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How is IMSI performed?

By Marta Barranquero Gómez B.Sc., M.Sc. (embryologist).
Last Update: 02/17/2025

The IMSI procedure is similar to ICSI. First, the semen is capacitated and prepared in the laboratory. The main difference between these two methods is the type of microscope used for sperm selection.

In the case of IMSI, a microscope with MSOME (Motile Sperm Organelle Morphology Examination) technology is used, which has a digital image processor.

Once the embryologist selects the optimal spermatozoa, they are transferred to the ICSI plate. A conventional microinjector is then used to fertilize the eggs in the same way as in ICSI.

Translated with DeepL.com (free version)

 Marta Barranquero Gómez
Marta Barranquero Gómez
B.Sc., M.Sc.
Embryologist
Graduated in Biochemistry and Biomedical Sciences by the University of Valencia (UV) and specialized in Assisted Reproduction by the University of Alcalá de Henares (UAH) in collaboration with Ginefiv and in Clinical Genetics by the University of Alcalá de Henares (UAH).
License: 3316-CV
Embryologist. Graduated in Biochemistry and Biomedical Sciences by the University of Valencia (UV) and specialized in Assisted Reproduction by the University of Alcalá de Henares (UAH) in collaboration with Ginefiv and in Clinical Genetics by the University of Alcalá de Henares (UAH). License: 3316-CV.