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Is it necessary to wait for the arrival of the period to make an AI?

By Zulyma Blanco Maldonado M.D., M.Sc. (fertility specialist on IVF Spain Donostia).
Last Update: 07/29/2021

Artificial insemination or AI is one of the best known treatments in Assisted Reproduction.

It is a simple and minimally invasive technique, which consists of introducing a semen sample into the mother's uterus. For this, it is important that ovulation is taking place at that moment, for which ovarian stimulation is often used. In addition, the sperm deposited are previously capacitated in the laboratory, i.e. those with the highest fertilisation potential are selected.

As in any fertility treatment, in Artificial Insemination (AI), the monitoring begins in the first three days of the menstrual period and ends with the pregnancy test in blood four weeks later.

The first day of the menstrual cycle is the day of heavy vaginal bleeding, where the hormone levels of oestrogen and progesterone should be low. This triggers the start of the hormonal cycle and the response of the pituitary gland in the brain to begin production of the follicle-stimulating hormone (FSH) necessary for follicle recruitment and subsequent ovulation.

Even with irregular hormonal cycles, the first day of the period marks the start of the menstrual cycle.

 Zulyma  Blanco Maldonado
Zulyma Blanco Maldonado
M.D., M.Sc.
Fertility specialist on IVF Spain Donostia
Dr. Zulyma Blanco has a degree in Medicine and a PhD from the Universidad Centro Occidental 'Lisandro Alvarado'. She also holds the title of Specialist in Infertility from the Central University of Venezuela and a Master's Degree in Infertility from the Complutense University of Madrid.
License: 202871721
Fertility specialist. Dr. Zulyma Blanco has a degree in Medicine and a PhD from the Universidad Centro Occidental 'Lisandro Alvarado'. She also holds the title of Specialist in Infertility from the Central University of Venezuela and a Master's Degree in Infertility from the Complutense University of Madrid. License: 202871721.