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What are the causes of repeated biochemical pregnancies?

By Marta Barranquero Gómez B.Sc., M.Sc. (embryologist).
Last Update: 11/21/2025

A biochemical pregnancy is an early loss of pregnancy that usually occurs a few days after a positive pregnancy test. It is quite difficult to determine the cause of biochemical pregnancies, since the embryonic tissue is expelled with menstruation and therefore cannot be analyzed.

Even so, in many cases, spontaneous miscarriages are due to problems with the embryo, possibly caused by low-quality sperm or eggs.

Other possible causes may include:

  • Abnormal hormone levels.
  • Uterine abnormalities.
  • Implantation outside the uterus, that is, ectopic pregnancies.
  • Sexually transmitted infections.
  • Advanced maternal age.
  • Blood clotting issues and thyroid disorders.

In any case, it is not recommended to try to identify the possible cause of the biochemical pregnancy. Some embryos are simply not capable of developing.

Imagen: Causes of recurrent biochemical pregnancy
Read the full article on: What are the main causes of miscarriage? ( 37).
 Marta Barranquero Gómez
Marta Barranquero Gómez
B.Sc., M.Sc.
Embryologist
Graduated in Biochemistry and Biomedical Sciences by the University of Valencia (UV) and specialized in Assisted Reproduction by the University of Alcalá de Henares (UAH) in collaboration with Ginefiv and in Clinical Genetics by the University of Alcalá de Henares (UAH).
License: 3316-CV
Embryologist. Graduated in Biochemistry and Biomedical Sciences by the University of Valencia (UV) and specialized in Assisted Reproduction by the University of Alcalá de Henares (UAH) in collaboration with Ginefiv and in Clinical Genetics by the University of Alcalá de Henares (UAH). License: 3316-CV.