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What are the symptoms of premenopause?

By Marta Barranquero Gómez B.Sc., M.Sc. (embryologist).
Last Update: 07/02/2026

Perimenopause, or premenopause, is the transitional stage leading up to menopause. This period typically occurs between the ages of 45 and 50.

Irregularities in the menstrual cycle during these years are the most common symptom of perimenopause. Menstrual changes at this stage are due to a decrease in the female sex hormones, estrogen and progesterone.

In addition to menstrual irregularities, women may also experience hot flashes, loss of sexual desire, abdominal bloating, etc.

 Marta Barranquero Gómez
Marta Barranquero Gómez
B.Sc., M.Sc.
Embryologist
Graduated in Biochemistry and Biomedical Sciences by the University of Valencia (UV) and specialized in Assisted Reproduction by the University of Alcalá de Henares (UAH) in collaboration with Ginefiv and in Clinical Genetics by the University of Alcalá de Henares (UAH).
License: 3316-CV
Embryologist. Graduated in Biochemistry and Biomedical Sciences by the University of Valencia (UV) and specialized in Assisted Reproduction by the University of Alcalá de Henares (UAH) in collaboration with Ginefiv and in Clinical Genetics by the University of Alcalá de Henares (UAH). License: 3316-CV.