The PICSI technique refers to what is known as physiological ICSI. This is a form of sperm selection prior to introduction into the egg.
It is based on the ability of the sperm to bind to hyaluronic acid, a substance that coats eggs. To do this, a special plate is used in which there are a few drops of a substance similar to hyaluronic acid that covers the eggs. Thus, the sperm capable of adhering to the plate will be those of the highest quality and potential for fertilization.