A primordial follicle can spend years in "quiescence" until it initiates its development. Subsequently, once initiated, it takes approximately 150 days for a primordial follicle to become a Graafian follicle. This means that the follicle that will ovulate in a given menstrual cycle began to develop about 5 menstrual cycles earlier, along with many other follicles that have been lost during their development due to atresia.
What is the duration of folliculogenesis?
By Silvia Azaña Gutiérrez (embryologist).
Last Update: 01/05/2022
Silvia Azaña Gutiérrez
Graduate in Health Biology from the University of Alcalá and specialized in Clinical Genetics from the same university. Master in Assisted Reproduction by the University of Valencia in collaboration with IVI clinics.