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What test is done to see if there are vacuoles in the sperm?

By Silvia Azaña Gutiérrez B.Sc., M.Sc. (embryologist).
Last Update: 06/30/2023

Vacuoles in the sperm head are detectable when spermatozoa are evaluated at high magnification, known as MSOME. In this case, spermatozoa are observed at more than 6000 magnification, which allows a very accurate assessment of their morphology.

When MSOME is performed to morphologically select the sperm to be microinjected in an ICSI, this modified ICSI is called IMSI.

 Silvia Azaña Gutiérrez
Silvia Azaña Gutiérrez
B.Sc., M.Sc.
Embryologist
Graduate in Health Biology from the University of Alcalá and specialized in Clinical Genetics from the same university. Master in Assisted Reproduction by the University of Valencia in collaboration with IVI clinics.
License: 3435-CV
Embryologist. Graduate in Health Biology from the University of Alcalá and specialized in Clinical Genetics from the same university. Master in Assisted Reproduction by the University of Valencia in collaboration with IVI clinics. License: 3435-CV.