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Which is better, chorion biopsy or amniocentesis?

By Óscar Oviedo Moreno M.D. (gynecologist on Fertility Madrid).
Last Update: 02/09/2022

Both are invasive prenatal diagnostic techniques. The gynecologist should be the one to indicate when to perform one or the other depending on the gestational age.

The earliest is a chorion biopsy, which can be performed between the 10th and 14th week of pregnancy. The risk of miscarriage is 7-8%. It is performed by removing a small sample of chorionic villi.

Amniocentesis can be done between 16-18 weeks of pregnancy. It is performed by extracting amniotic fluid. The risk of miscarriage with this technique is 0.6 and 1%.

Both present a risk of natural termination of pregnancy.

 Óscar Oviedo Moreno
Óscar Oviedo Moreno
M.D.
Gynecologist on Fertility Madrid
Bachelor's Degree in Medicine & Surgery from the University of Caldas (Colombia). Specialist in Internal Medicine by the Pontificia Universidad Javeriana of Bogotá. Degree standardized in Spain in 2003. Specialist in Gynecology & Obstetrics from the Complutense University of Madrid, with residence at Hospital Clínico Universitario San Carlos de Madrid. Expert in Reproductive Medicine and Certification in Obstetric-Gynecologic Ultrasound (levels I, II and III).
License: 282858310
Gynecologist. Bachelor's Degree in Medicine & Surgery from the University of Caldas (Colombia). Specialist in Internal Medicine by the Pontificia Universidad Javeriana of Bogotá. Degree standardized in Spain in 2003. Specialist in Gynecology & Obstetrics from the Complutense University of Madrid, with residence at Hospital Clínico Universitario San Carlos de Madrid. Expert in Reproductive Medicine and Certification in Obstetric-Gynecologic Ultrasound (levels I, II and III). License: 282858310.