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Why does IVF fail with donor eggs?

By Cristina Mestre Ferrer B.Sc., M.Sc. (embryologist).
Last Update: 05/29/2017

On average, the chances of success with donor-egg IVF are as high as 60% per transfer, since egg donors are young and healthy women with a high reproductive potential.

But egg quality is not the only factor influencing the outcome of this treatment. The patient's uterine conditions and sperm quality, among others, are also key factors when trying to get pregnant with donor eggs.

In some cases, however, in spite of transferring high-quality embryos and having a good endometrial receptivity, the embryos are still unable to implant for no apparent reason.

If you have gone through multiple failed IVF with donor eggs, the likelihood or risk for RIF or recurrent miscarriage with donor eggs depends on the cause behind your previous miscarriages. When it is caused by uterine abnormalities, using donor eggs will not change the situation to a large extent.

 Cristina Mestre Ferrer
Cristina Mestre Ferrer
B.Sc., M.Sc.
Embryologist
Bachelor's Degree in Biological Sciences, Genetics & Human Reproduction from the University of Valencia (UV). Master's Degree in Biotechnology of Human Assisted Reproduction from the UV and the Valencian Infertility Institute (IVI). Embryologist at IVI Barcelona.
Embryologist. Bachelor's Degree in Biological Sciences, Genetics & Human Reproduction from the University of Valencia (UV). Master's Degree in Biotechnology of Human Assisted Reproduction from the UV and the Valencian Infertility Institute (IVI). Embryologist at IVI Barcelona.