The effect of advanced maternal age is much better known, but the passage of time and age also have an effect on male fertility, although less pronounced.
From the age of 40-45, there are certain changes in sperm quality, such as an increase in its DNA fragmentation, greater oxidative stress, and certain epigenetic changes.
Read the full article on: Paternal age and assisted reproduction: its impact and advice ( 37).
By Silvia Azaña Gutiérrez B.Sc., M.Sc. (embryologist).
Last Update: 04/08/2026
