Diagnosis of Sertoli syndrome

Sertoli-only syndrome is characterized by the fact that the testicular seminiferous tubules have only Sertoli cells and therefore lack germ cells. This syndrome is diagnosed by histological analysis of tissue obtained from a male testicular biopsy.

The absence of germ cells in the seminiferous tubules means that there is no sperm production. Therefore, these males are azoospermic and, on many occasions, must resort to sperm donation to become fathers.